RCSB Protein Data Bank (RCSB.org): delivery of experimentally-determined PDB structures alongside one million computed structure models of proteins from artificial intelligence/machine learning

The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), founding member of the Worldwide Protein Data Bank (wwPDB), is the US data center for the open-access PDB archive. As wwPDB-designated Archive Keeper, RCSB PDB is also responsible for PDB data security. Annually, RCSB PDB serves >10 000 depositors of three-dimensional (3D) biostructures working on all permanently inhabited continents. RCSB PDB delivers data from its research-focused RCSB.org web portal to many millions of PDB data consumers based in virtually every United Nations-recognized country, territory, etc. This Database Issue contribution describes upgrades to the research-focused RCSB.org web portal that created a…

• NS
  National Science Foundation

  Awards: DBI-1832184, DBI-1756248, DBI-2112966
• UD
  U.S. Department of Energy

  Award: DE-SC0019749
• NI
  National Institutes of Health

  Award: R01GM133198
• BA
  Biotechnology and Biological Sciences Research Council

  Award: BB/W017970/1
• NC
  National Cancer Institute
• NI
  National Institute of Allergy and Infectious Diseases