The Role of Adipokines in Inflammatory Mechanisms of Obesity
National Medical Research Center of Cardiology · Russian Scientific Center of Surgery · +2 more institutions
Abstract
Adipokines are currently widely studied cellular signaling proteins produced by adipose tissue and involved in various processes, including inflammation; energy and appetite modulation; lipid and glucose metabolism; insulin sensitivity; endothelial cell functioning; angiogenesis; the regulation of blood pressure; and hemostasis. The current review attempted to highlight the key functions of adipokines in the inflammatory mechanisms of obesity, its complications, and its associated diseases. An extensive search for materials on the role of adipokines in the pathogenesis of obesity was conducted online using the PubMed and Scopus databases until October 2022.
Citation impact
- FWCI
- 32.75
- Percentile
- 100%
- References
- 166
Authors
6- TVTatiana V. Kirichenko
National Medical Research Center of Cardiology, Russian Scientific Center of Surgery
- YVYuliya V. MarkinaCorresponding
Russian Scientific Center of Surgery
- AIAnastasia I. Bogatyreva
Russian Scientific Center of Surgery
- TVTaisiya V. Tolstik
Russian Scientific Center of Surgery
- YVY. Varaeva
Federal Research Centre of Nutrition and Biotechnology
Topics & keywords
- Adipokine
- Adipose tissue
- Inflammation
- Angiogenesis
- Medicine
- Insulin resistance
- Obesity
- Bioinformatics
- Good health and well-being