articleJAMADec 12, 2022Closed access

Target Trial Emulation

MAMiguel A. HernánWWWei WangDEDavid E. Leaf

Harvard University · Brigham and Women's Hospital

PubMed
Indexed incrossrefpubmed

Abstract

This Guide to Statistics and Methods describes the use of target trial emulation to design an observational study so it preserves the advantages of a randomized clinical trial, points out the limitations of the method, and provides an example of its use.

Citation impact

804
total citations
FWCI
184.03
Percentile
100%
References
10
Citations per year

Authors

3

Topics & keywords

Topics
Keywords
  • Medicine
  • Emulation
  • Observational study
  • Randomized controlled trial
  • Medical physics
  • Clinical trial
  • Surgery
  • Internal medicine
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