Association of wearable device-measured vigorous intermittent lifestyle physical activity with mortality

Wearable devices can capture unexplored movement patterns such as brief bursts of vigorous intermittent lifestyle physical activity (VILPA) that is embedded into everyday life, rather than being done as leisure time exercise. Here, we examined the association of VILPA with all-cause, cardiovascular disease (CVD) and cancer mortality in 25,241 nonexercisers (mean age 61.8 years, 14,178 women/11,063 men) in the UK Biobank. Over an average follow-up of 6.9 years, during which 852 deaths occurred, VILPA was inversely associated with all three of these outcomes in a near-linear fashion. Compared with participants who engaged in no VILPA, participants who engaged in VILPA at the sample median VILPA frequency of 3…

• W
  Wellcome

  Award: 223100/Z/21/Z
• WT
  Wellcome Trust

  Award: 223100/Z/21/Z
• AT
  Alan Turing Institute

  Award: SP/18/4/33803
• UR
  UK Research and Innovation
• NI
  National Institute for Health and Care Research
• BH
  British Heart Foundation

  Awards: RE/18/3/34214, SP/18/4/33803
• DO
  Department of Health and Social Care
• NN
  Novo Nordisk
• MR
  Medical Research Council

  Award: MC_PC_17228
• NH
  National Health and Medical Research Council

  Awards: APP 1194510, APP1194510, APP1180812