Non-Alcoholic Fatty Liver Disease (NAFLD) Pathogenesis and Natural Products for Prevention and Treatment
Chinese Academy of Sciences · Changchun Institute of Applied Chemistry · +2 more institutions
Abstract
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease, affecting approximately one-quarter of the global population, and has become a world public health issue. NAFLD is a clinicopathological syndrome characterized by hepatic steatosis, excluding ethanol and other definite liver damage factors. Recent studies have shown that the development of NAFLD is associated with lipid accumulation, oxidative stress, endoplasmic reticulum stress, and lipotoxicity. A range of natural products have been reported as regulators of NAFLD in vivo and in vitro. This paper reviews the pathogenesis of NAFLD and some natural products that have been shown to have therapeutic effects on NAFLD. Our work…
Citation impact
- FWCI
- 50.31
- Percentile
- 100%
- References
- 125
Authors
4- XGXiangyu Guo
Chinese Academy of Sciences, Changchun Institute of Applied Chemistry, Changchun University of Chinese Medicine
- XYXunzhe Yin
Chinese Academy of Sciences, Changchun Institute of Applied Chemistry
- ZLZuojia LiuCorresponding
Chinese Academy of Sciences, Changchun Institute of Applied Chemistry
- JWJin WangCorresponding
Stony Brook University
Topics & keywords
- Fatty liver
- Lipotoxicity
- Steatosis
- Medicine
- Pathogenesis
- Oxidative stress
- Internal medicine
- Chronic liver disease
- Good health and well-being