reviewJournal of Extracellular VesiclesDec 1, 2022GOLD OA

Plant‐derived extracellular vesicles: Recent advancements and current challenges on their use for biomedical applications

National University of Singapore · National University Cancer Institute, Singapore · +3 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Extracellular vesicles (EVs) represent a diverse class of lipid bilayer membrane vesicles released by both animal and plant cells. These ubiquitous vesicles are involved in intercellular communication and transport of various biological cargos, including proteins, lipids, and nucleic acids. In recent years, interest in plant-derived EVs has increased tremendously, as they serve as a scalable and sustainable alternative to EVs derived from mammalian sources. In vitro and in vivo findings have demonstrated that these plant-derived vesicles (PDVs) possess intrinsic therapeutic activities that can potentially treat diseases and improve human health. In addition, PDVs can also act as efficient and biocompatible…

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