reviewInternational Journal of Molecular SciencesDec 29, 2022GOLD OA

Selected Biomarkers of Depression: What Are the Effects of Cytokines and Inflammation?

Comenius University Bratislava

PubMed
Indexed incrossrefpubmed

Abstract

Depression is one of the leading mental illnesses worldwide and lowers the quality of life of many. According to WHO, about 5% of the worldwide population suffers from depression. Newer studies report a staggering global prevalence of 27.6%, and it is rising. Professionally, depression belonging to affective disorders is a psychiatric illness, and the category of major depressive disorder (MDD) comprises various diagnoses related to persistent and disruptive mood disorders. Due to this fact, it is imperative to find a way to assess depression quantitatively using a specific biomarker or a panel of biomarkers that would be able to reflect the patients' state and the effects of therapy. Cytokines, hormones,…

Citation impact

275
total citations
FWCI
15.24
Percentile
100%
References
221
Citations per year

Authors

4

Topics & keywords

Keywords
  • Inflammation
  • Depression (economics)
  • Proinflammatory cytokine
  • Medicine
  • Immunology
  • Tumor necrosis factor alpha
UN Sustainable Development Goals
  • Good health and well-being
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