Extracellular vesicle-loaded hydrogels for tissue repair and regeneration
Central South University · Second Xiangya Hospital of Central South University · +1 more institution
Abstract
Extracellular vesicles (EVs) are a collective term for nanoscale or microscale vesicles secreted by cells that play important biological roles. Mesenchymal stem cells are a class of cells with the potential for self-healing and multidirectional differentiation. In recent years, numerous studies have shown that EVs, especially those secreted by mesenchymal stem cells, can promote the repair and regeneration of various tissues and, thus, have significant potential in regenerative medicine. However, due to the rapid clearance capacity of the circulatory system, EVs are barely able to act persistently at specific sites for repair of target tissues. Hydrogels have good biocompatibility and loose and porous…
Citation impact
- FWCI
- 32.22
- Percentile
- 100%
- References
- 290
Authors
5- YJYikun Ju
Central South University, Second Xiangya Hospital of Central South University
- YHYue Hu
North Sichuan Medical University
- YPYang Pu
Central South University, Second Xiangya Hospital of Central South University
- XXXiaoyan Xie
Central South University, Second Xiangya Hospital of Central South University
- BFBairong FangCorresponding
Central South University, Second Xiangya Hospital of Central South University
Topics & keywords
- Self-healing hydrogels
- Regeneration (biology)
- Extracellular vesicles
- Regenerative medicine
- Mesenchymal stem cell
- Nanotechnology
- Microscale chemistry
- Tissue engineering