reviewPhysiological ReviewsJan 5, 2023GREEN OA

The molecular athlete: exercise physiology from mechanisms to medals

University of Basel · Australian Catholic University

PubMed
Indexed incrossrefpubmed

Abstract

Human skeletal muscle demonstrates remarkable plasticity, adapting to numerous external stimuli including the habitual level of contractile loading. Accordingly, muscle function and exercise capacity encompass a broad spectrum, from inactive individuals with low levels of endurance and strength to elite athletes who produce prodigious performances underpinned by pleiotropic training-induced muscular adaptations. Our current understanding of the signal integration, interpretation, and output coordination of the cellular and molecular mechanisms that govern muscle plasticity across this continuum is incomplete. As such, training methods and their application to elite athletes largely rely on a "trial-and-error"…

Citation impact

194
total citations
FWCI
59.64
Percentile
100%
References
878
Citations per year

Authors

3

Topics & keywords

Keywords
  • Athletes
  • Context (archaeology)
  • Endurance training
  • Elite athletes
  • Adaptive response
  • Skeletal muscle
  • Adaptation (eye)
  • Exercise physiology
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