reviewAnnual Review of Plant BiologyJan 6, 2023HYBRID OA

cis -Regulatory Elements in Plant Development, Adaptation, and Evolution

University of Georgia · Donald Danforth Plant Science Center · +2 more institutions

PubMed
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Abstract

Cis-Regulatory elements encode the genomic blueprints that ensure the proper spatiotemporal patterning of gene expression necessary for appropriate development and responses to the environment. Accumulating evidence implicates changes to gene expression as a major source of phenotypic novelty in eukaryotes, including acute phenotypes such as disease and cancer in mammals. Moreover, genetic and epigenetic variation affecting cis-regulatory sequences over longer evolutionary timescales has become a recurring theme in studies of morphological divergence and local adaptation. Here, we discuss the functions of and methods used to identify various classes of cis-regulatory elements, as well as their role in plant…

Citation impact

299
total citations
FWCI
112.74
Percentile
100%
References
163
Citations per year

Authors

4

Topics & keywords

Keywords
  • Biology
  • Adaptation (eye)
  • Epigenetics
  • Novelty
  • Gene
  • Regulation of gene expression
  • Gene regulatory network
  • Evolutionary biology
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