reviewAdvanced MaterialsJan 9, 2023Closed access

Biosystem‐Inspired Engineering of Nanozymes for Biomedical Applications

University of Science and Technology of China · Chinese Academy of Sciences · +1 more institution

PubMed
Indexed incrossrefpubmed

Abstract

Nanozymes with intrinsic enzyme-mimicking activities have shown great potential to become surrogates of natural enzymes in many fields by virtue of their advantages of high catalytic stability, ease of functionalization, and low cost. However, due to the lack of predictable descriptors, most of the nanozymes reported in the past have been obtained mainly through trial-and-error strategies, and the catalytic efficacy, substrate specificity, as well as practical application effect under physiological conditions, are far inferior to that of natural enzymes. To optimize the catalytic efficacies and functions of nanozymes in biomedical settings, recent studies have introduced biosystem-inspired strategies into…

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