articlePLoS MedicineJan 10, 2023GOLD OA

Healthy lifestyle behaviors, mediating biomarkers, and risk of microvascular complications among individuals with type 2 diabetes: A cohort study

TGTingting GengKZKai ZhuQLQi LuZWZhenzhen WanXCXue Chen

Huazhong University of Science and Technology

PubMed
Indexed incrossrefdoajpubmed

Abstract

BACKGROUND: The influence of overall lifestyle behaviors on diabetic microvascular complications remains unknown. In addition, the potential mediating biomarkers underlying the association is unclear. This study aimed to examine the associations of the combined lifestyle factors with risks of total and individual microvascular complications among patients with type 2 diabetes (T2D) and to explore the potential mediation effects of metabolic biomarkers. METHODS AND FINDINGS: This retrospective cohort study included 15,104 patients with T2D free of macro- and microvascular complications at baseline (2006 to 2010) from the UK Biobank. Healthy lifestyle behaviors included noncurrent smoking, recommended waist…

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192
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34.83
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100%
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Authors

8

Topics & keywords

Topics
Keywords
  • Medicine
  • Internal medicine
  • Diabetes mellitus
  • Type 2 diabetes
  • Hazard ratio
  • Cohort study
  • Glycemic
  • Cohort
UN Sustainable Development Goals
  • Good health and well-being
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