revieweLifeJan 18, 2023GOLD OA

Transformer-based deep learning for predicting protein properties in the life sciences

Umeå University · Swedish University of Agricultural Sciences · +1 more institution

PubMed
Indexed incrossrefdoajpubmed

Abstract

Recent developments in deep learning, coupled with an increasing number of sequenced proteins, have led to a breakthrough in life science applications, in particular in protein property prediction. There is hope that deep learning can close the gap between the number of sequenced proteins and proteins with known properties based on lab experiments. Language models from the field of natural language processing have gained popularity for protein property predictions and have led to a new computational revolution in biology, where old prediction results are being improved regularly. Such models can learn useful multipurpose representations of proteins from large open repositories of protein sequences and can be…

Citation impact

182
total citations
FWCI
26.46
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100%
References
187
Citations per year

Authors

4

Topics & keywords

Keywords
  • Deep learning
  • Artificial intelligence
  • Computer science
  • Transformer
  • Machine learning
  • Protein structure prediction
  • Popularity
  • Computational biology
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