articleAnnals of SurgeryJan 20, 2023HYBRID OA

Locoregional Failure During and After Short-course Radiotherapy Followed by Chemotherapy and Surgery Compared With Long-course Chemoradiotherapy and Surgery

University Medical Center Groningen · University of Groningen · +10 more institutions

PubMed
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Abstract

Objective

To analyze risk and patterns of locoregional failure (LRF) in patients of the RAPIDO trial at 5 years.

Background

Multimodality treatment improves local control in rectal cancer. Total neoadjuvant treatment (TNT) aims to improve systemic control while local control is maintained. At 3 years, LRF rate was comparable between TNT and chemoradiotherapy in the RAPIDO trial.

Citation impact

335
total citations
FWCI
72.09
Percentile
100%
References
19
Citations per year

Authors

18

Topics & keywords

Keywords
  • Medicine
  • Radiation therapy
  • Chemoradiotherapy
  • Hazard ratio
  • Chemotherapy
  • Surgery
  • Colorectal cancer
  • Lymph node
UN Sustainable Development Goals
  • Good health and well-being
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Funding