Reshaping the Endogenous Electric Field to Boost Wound Repair via Electrogenerative Dressing
Army Medical University · Chinese Academy of Sciences · +8 more institutions
Abstract
The endogenous electric field (EF) generated by transepithelial potential difference plays a decisive role in wound reepithelialization. For patients with large or chronic wounds, negative-pressure wound therapy (NPWT) is the most effective clinical method in inflammation control by continuously removing the necrotic tissues or infected substances, thus creating a proproliferative microenvironment beneficial for wound reepithelialization. However, continuous negative-pressure drainage causes electrolyte loss and weakens the endogenous EF, which in turn hinders wound reepithelialization. Here, an electrogenerative dressing (EGD) is developed by integrating triboelectric nanogenerators with NPWT. By converting…
Citation impact
- FWCI
- 22.75
- Percentile
- 100%
- References
- 45
Authors
17- RLRuizeng Luo
Army Medical University, Chinese Academy of Sciences, Southwest Hospital, Beijing Institute of Nanoenergy and Nanosystems, University of Chinese Academy of Sciences
- YLYi Liang
Army Medical University, Military Hospital, Southwest Hospital
- JYJinrui Yang
Army Medical University, Southwest Hospital
- HFHongqing Feng
Chinese Academy of Sciences, Beijing Institute of Nanoenergy and Nanosystems, University of Chinese Academy of Sciences
- YCYing Chen
Army Medical University, Southwest Hospital
Topics & keywords
- Wound healing
- Negative-pressure wound therapy
- Medicine
- Inflammation
- Extracellular matrix
- Granulation tissue
- Endogeny
- Surgery