preprintDrug Discovery TodayJan 22, 2026HYBRID OA

The statistical software revolution in pharmaceutical development: challenges and opportunities in open source

Dornier Flugzeugwerke (Germany) · Bavarian Academy of Sciences and Humanities · +10 more institutions

PubMed
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Abstract

• 1. Viraswami-Appanna et al. (2024). Accelerating drug development at Bristol Myers Squibb through innovation. Drug Discov Today. • 2. Cook et al. (2014). Lessons from the fate of AstraZeneca’s drug pipeline. Nat Rev Drug Discov. • 3. Pammolli et al. (2011). The productivity crisis in pharmaceutical R&D. Nat Rev Drug Discov. • 4. Laermann-Nguyen & Backfisch (2021). Innovation crisis in the pharmaceutical industry? SN Bus Econ.5. Schlander et al. (2021). Cost of researching and developing a new drug: A systematic review. Pharmacoeconomics. Open-source statistical software development is increasingly the preferred solution for leveraging new statistical methods in the pharmaceutical industry. However, with a…

Citation impact

5
total citations
FWCI
44.20
Percentile
99%
References
24
Citations per year

Authors

12

Topics & keywords

Keywords
  • Software engineering
  • Software development
  • Software construction
  • Computer science
  • Personal software process
  • Social software engineering
  • Software peer review
  • Software
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