reviewAdvanced ScienceFeb 1, 2023GOLD OA

Advances of Antimicrobial Peptide‐Based Biomaterials for the Treatment of Bacterial Infections

GLGuoyu LiZLZhenheng LaiASAnshan Shan

Northeast Agricultural University

PubMed
Indexed incrossrefdoajpubmed

Abstract

Owing to the increase in multidrug-resistant bacterial isolates in hospitals globally and the lack of truly effective antimicrobial agents, antibiotic resistant bacterial infections have increased substantially. There is thus an urgent need to develop new antimicrobial drugs and their related formulations. In recent years, natural antimicrobial peptides (AMPs), AMP optimization, self-assembled AMPs, AMP hydrogels, and biomaterial-assisted delivery of AMPs have shown great potential in the treatment of bacterial infections. In this review, it is focused on the development prospects and shortcomings of various AMP-based biomaterials for treating animal model infections, such as abdominal, skin, and eye…

Citation impact

188
total citations
FWCI
32.75
Percentile
100%
References
189
Citations per year

Authors

3

Topics & keywords

Topics
Keywords
  • Antimicrobial
  • Peptide
  • Microbiology
  • Antimicrobial peptides
  • Chemistry
  • Medicine
  • Biology
  • Biochemistry
No related works found for this paper.

Funding