Silver Nanoparticles: Bactericidal and Mechanistic Approach against Drug Resistant Pathogens
University of Campania "Luigi Vanvitelli" · Chalmers University of Technology · +3 more institutions
Abstract
This review highlights the different modes of synthesizing silver nanoparticles (AgNPs) from their elemental state to particle format and their mechanism of action against multidrug-resistant and biofilm-forming bacterial pathogens. Various studies have demonstrated that the AgNPs cause oxidative stress, protein dysfunction, membrane disruption, and DNA damage in bacteria, ultimately leading to bacterial death. AgNPs have also been found to alter the adhesion of bacterial cells to prevent biofilm formation. The benefits of using AgNPs in medicine are, to some extent, counter-weighted by their toxic effect on humans and the environment. In this review, we have compiled recent studies demonstrating the…
Citation impact
- FWCI
- 57.72
- Percentile
- 100%
- References
- 240
Authors
6- PRPragati Rajendra More
University of Campania "Luigi Vanvitelli", Chalmers University of Technology
- SPSantosh Pandit
Chalmers University of Technology
- ADAnna De Filippis
University of Campania "Luigi Vanvitelli"
- GFGianluigi Franci
University of Salerno
- IMIvan Mijakovic̀Corresponding
Novo Nordisk Foundation, Chalmers University of Technology, Technical University of Denmark
Topics & keywords
- Silver nanoparticle
- Biofilm
- Microbiology
- Chemistry
- Pathogenicity
- Nanotechnology
- Mechanism of action
- Drug
- Good health and well-being