articleNature CommunicationsFeb 3, 2023GOLD OA

Atlas of plasma NMR biomarkers for health and disease in 118,461 individuals from the UK Biobank

Nightingales Medical Trust · Nightingale Hospital · +1 more institution

PubMed
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Abstract

Blood lipids and metabolites are markers of current health and future disease risk. Here, we describe plasma nuclear magnetic resonance (NMR) biomarker data for 118,461 participants in the UK Biobank. The biomarkers cover 249 measures of lipoprotein lipids, fatty acids, and small molecules such as amino acids, ketones, and glycolysis metabolites. We provide an atlas of associations of these biomarkers to prevalence, incidence, and mortality of over 700 common diseases ( nightingalehealth.com/atlas ). The results reveal a plethora of biomarker associations, including susceptibility to infectious diseases and risk of various cancers, joint disorders, and mental health outcomes, indicating that abundant…

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513
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Authors

16

Topics & keywords

Keywords
  • Biobank
  • Biomarker
  • Biomarker discovery
  • Disease
  • Medicine
  • Metabolomics
  • Bioinformatics
  • Computational biology
UN Sustainable Development Goals
  • Good health and well-being
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