ATM orchestrates ferritinophagy and ferroptosis by phosphorylating NCOA4
Huazhong Agricultural University · Nankai University
Indexed incrossrefpubmed
Abstract
AMPK: AMP-activated protein kinase; ATM: ataxia telangiectasia mutated; BSO: buthionine sulphoximine; CDKN1A: cyclin-dependent kinase inhibitor 1A (P21); CQ: chloroquine; DFO: deferoxamine; DFP: deferiprone; Fer: ferrostatin-1; FTH1: ferritin heavy polypeptide 1; GPX4: glutathione peroxidase 4; GSH: glutathione; MEF: mouse embryonic fibroblast; NCOA4: nuclear receptor coactivator 4; PFTα: pifithrin-α; PTGS2: prostaglandin-endoperoxide synthase 2; Slc7a11: solute carrier family 7 member 11; Sul: sulfasalazine; TFRC: transferrin receptor; TRP53: transformation related protein 53.
Citation impact
211
total citations
- FWCI
- 51.05
- Percentile
- 100%
- References
- 76
Citations per year
Authors
5Topics & keywords
Topics
Keywords
- Biology
- Autophagy
- Programmed cell death
- Cell biology
- DNA damage
- Kinase
- Transferrin receptor
- Protein kinase A
UN Sustainable Development Goals
- Good health and well-being
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