reviewiScienceJan 28, 2023GOLD OA

Recent insights into uptake, toxicity, and molecular targets of microplastics and nanoplastics relevant to human health impacts

University of North Carolina at Greensboro

PubMed
Indexed incrossrefdoajpubmed

Abstract

Microplastics and nanoplastics (M-NPLs) are ubiquitous environmentally, chemically, or mechanically degraded plastic particles. Humans are exposed to M-NPLs of various sizes and types through inhalation of contaminated air, ingestion of contaminated water and food, and other routes. It is estimated that Americans ingest tens of thousands to millions of M-NPLs particles yearly, depending on socioeconomic status, age, and gender. M-NPLs have spurred interest in toxicology because of their abundance, ubiquitous nature, and ability to penetrate bodily and cellular barriers, producing toxicological effects in cells, tissues, organs, and organ systems. The present review paper highlights: (1) The current knowledge…

Citation impact

213
total citations
FWCI
14.65
Percentile
100%
References
261
Citations per year

Authors

2

Topics & keywords

Keywords
  • Microplastics
  • Toxicity
  • Endocytosis
  • Cell biology
  • Biology
  • Nanotoxicology
  • Reactive oxygen species
  • Chemistry
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Funding