articleNucleic Acids ResearchNov 29, 2011GOLD OA

The Pfam protein families database

Wellcome Sanger Institute

Indexed incrossrefdoaj

Abstract

Pfam is a widely used database of protein families, currently containing more than 13,000 manually curated protein families as of release 26.0. Pfam is available via servers in the UK (http://pfam.sanger.ac.uk/), the USA (http://pfam.janelia.org/) and Sweden (http://pfam.sbc.su.se/). Here, we report on changes that have occurred since our 2010 NAR paper (release 24.0). Over the last 2 years, we have generated 1840 new families and increased coverage of the UniProt Knowledgebase (UniProtKB) to nearly 80%. Notably, we have taken the step of opening up the annotation of our families to the Wikipedia community, by linking Pfam families to relevant Wikipedia pages and encouraging the Pfam and Wikipedia communities…

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Authors

16

Topics & keywords

Keywords
  • UniProt
  • Annotation
  • Biology
  • Protein family
  • Computational biology
  • Function (biology)
  • Database
  • Bioinformatics
UN Sustainable Development Goals
  • Quality Education
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