reviewInternational Journal of Molecular SciencesFeb 14, 2023GOLD OA

Inflammatory Bowel Diseases and Gut Microbiota

Tokyo University of Agriculture and Technology · Sapienza University of Rome · +2 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Inflammatory bowel disease (IBD) is an inflammatory disease of the gastrointestinal tract, the incidence of which has rapidly increased worldwide, especially in developing and Western countries. Recent research has suggested that genetic factors, the environment, microbiota, and immune responses are involved in the pathogenesis; however, the underlying causes of IBD are unclear. Recently, gut microbiota dysbiosis, especially a decrease in the abundance and diversity of specific genera, has been suggested as a trigger for IBD-initiating events. Improving the gut microbiota and identifying the specific bacterial species in IBD are essential for understanding the pathogenesis and treatment of IBD and autoimmune…

Citation impact

222
total citations
FWCI
32.55
Percentile
100%
References
111
Citations per year

Authors

6

Topics & keywords

Keywords
  • Dysbiosis
  • Gut flora
  • Inflammatory bowel disease
  • Pathogenesis
  • Immunology
  • Biology
  • Gastrointestinal tract
  • Disease
UN Sustainable Development Goals
  • Partnerships for the goals
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Funding