articleJournal of Materials Research and TechnologyFeb 15, 2023GOLD OA

Review on magnesium and magnesium-based alloys as biomaterials for bone immobilization

University of Shanghai for Science and Technology · Shanghai Children's Medical Center

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Abstract

Magnesium alloy has become one of the third-generation biomedical materials to promote bone tissue regeneration. Compared to other metal implants, magnesium metal is biodegradable and continues to degrade as the bone tissue heals, eliminating the need for secondary surgical removal. The Young's modulus of magnesium alloys is closer to human bone, and the magnesium ions produced by degradation are osteoinductive and antimicrobial, which can stimulate new bone formation, diminish stress shielding effects and reduce the risk of implant failure due to infection. However, the rapid corrosion rate of pure magnesium in a physiological environment can result in the mechanical integrity of the implant being compromised…

Citation impact

177
total citations
FWCI
16.89
Percentile
100%
References
209
Citations per year

Authors

5

Topics & keywords

Keywords
  • Magnesium
  • Materials science
  • Biocompatibility
  • Corrosion
  • Bone healing
  • Metallurgy
  • Implant
  • Bone tissue
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