reviewAdvanced MaterialsFeb 16, 2023BRONZE OA

Ceria‐Based Therapeutic Antioxidants for Biomedical Applications

Seoul National University · Institute for Basic Science · +4 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

The growing interest in nanomedicine over the last 20 years has carved out a research field called "nanocatalytic therapy," where catalytic reactions mediated by nanomaterials are employed to intervene in disease-critical biomolecular processes. Among many kinds of catalytic/enzyme-mimetic nanomaterials investigated thus far, ceria nanoparticles stand out from others owing to their unique scavenging properties against biologically noxious free radicals, including reactive oxygen species (ROS) and reactive nitrogen species (RNS), by exerting enzyme mimicry and nonenzymatic activities. Much effort has been made to utilize ceria nanoparticles as self-regenerating antioxidative and anti-inflammatory agents for…

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