The Gene Ontology knowledgebase in 2023
University of Southern California · SIB Swiss Institute of Bioinformatics · +5 more institutions
Abstract
The Gene Ontology (GO) knowledgebase (http://geneontology.org) is a comprehensive resource concerning the functions of genes and gene products (proteins and noncoding RNAs). GO annotations cover genes from organisms across the tree of life as well as viruses, though most gene function knowledge currently derives from experiments carried out in a relatively small number of model organisms. Here, we provide an updated overview of the GO knowledgebase, as well as the efforts of the broad, international consortium of scientists that develops, maintains, and updates the GO knowledgebase. The GO knowledgebase consists of three components: (1) the GO-a computational knowledge structure describing the functional…
Citation impact
- FWCI
- 393.32
- Percentile
- 100%
- References
- 72
Authors
312- SASuzi Aleksander
University of Southern California, SIB Swiss Institute of Bioinformatics, University of Padua, Phoenix Bioinformatics, University College London, University at Buffalo, State University of New York, Stanford University
- JPJames P. Balhoff
University of Southern California, SIB Swiss Institute of Bioinformatics, University of Padua, Phoenix Bioinformatics, University College London, University at Buffalo, State University of New York, Stanford University
- SCSeth Carbon
University of Southern California, SIB Swiss Institute of Bioinformatics, University of Padua, Phoenix Bioinformatics, University College London, University at Buffalo, State University of New York, Stanford University
- JMJ. Michael Cherry
University of Southern California, SIB Swiss Institute of Bioinformatics, University of Padua, Phoenix Bioinformatics, University College London, University at Buffalo, State University of New York, Stanford University
- HDHarold Drabkin
University of Southern California, SIB Swiss Institute of Bioinformatics, University of Padua, Phoenix Bioinformatics, University College London, University at Buffalo, State University of New York, Stanford University
Topics & keywords
- Gene nomenclature
- Ontology
- Function (biology)
- Computational biology
- Biology
- Gene ontology
- Resource (disambiguation)
- Gene
Funding
- NSNational Science FoundationAwards: BB/S01781X/1, 1340112, DE-AC02-05CH11231
- UDU.S. Department of EnergyAwards: -AC02-05CH11231, 05CH11231, AC02-05CH11231, DE-AC02, DE-AC02-05CH11231, DE-AC02-
- UDU.S. Department of AgricultureAward: DE-AC02-05CH11231
- WTWellcome TrustAwards: 218236/Z/19/Z, U24HG002223, P41 HD064556
- EMEuropean Molecular Biology Laboratory
- AGAustralian Government
- NINational Institute for Health and Care Research
- UCUniversity College London
- NINational Institutes of HealthAwards: U24HG010859, U24HG002223, U41HG000739, U41HG002273, P41 HD064556, U24HG001315, R01HL064541, U24HG007822, U24HG012198, DE-AC02-05CH11231, U24HG011851
- DFDirectorate for Biological SciencesAwards: 1340112, 1127112
- OOOffice of ScienceAwards: AC02-05CH11231, -AC02-05CH11231, DE-AC02
- ARAgricultural Research Service
- MRMedical Research CouncilAwards: MR/W024233/1, MR/N030117/1, DE-AC02-05CH11231, MR/W024233/1
- BABiotechnology and Biological Sciences Research CouncilAwards: BB/T010541/1, BBS/E/RH/230001B, BB/T000481/1, BB/S01781X/1, BB/T010541/1
- SFStaatssekretariat für Bildung, Forschung und Innovation
- NINational Institute on AgingAward: U24HG007822
- NHNational Heart, Lung, and Blood InstituteAwards: R01HL064541, U24HG007822, U24HG010859
- NHNational Human Genome Research InstituteAwards: U24HG012198, U24HG010859, U41HG002273, DE-AC02-05CH11231, U24HG000330, U24HG001315, U24HG002659, U24HG011851, R01HL064541, U24HG007822, U24HG002223, U24HG012212, U41HG000739
- NENational Eye InstituteAward: U24HG007822
- NCNational Cancer InstituteAwards: DE-AC02-05CH11231, U24HG007822
- NINational Institute of General Medical SciencesAwards: DE-AC02-05CH11231, U24HG007822
- NINational Institute of Allergy and Infectious DiseasesAward: U24HG007822
- NINational Institute of Diabetes and Digestive and Kidney DiseasesAward: U24HG007822
- NINational Institute of Child Health and Human Development
- BEBasic Energy SciencesAwards: DE-AC02, AC02-05CH11231, DE-AC02-05CH11231, -AC02-05CH11231
- EKEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentAward: P41 HD064556