articleMolecular Biology and EvolutionMar 1, 2023GOLD OA

Global Dynamics of Porcine Enteric Coronavirus PEDV Epidemiology, Evolution, and Transmission

HZHao ZhangCZChuangchao ZouOPOuyang PengUAUsama AshrafQXQiuping Xu

Sun Yat-sen University · Huazhong Agricultural University · +5 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

With a possible origin from bats, the alphacoronavirus Porcine epidemic diarrhea virus (PEDV) causes significant hazards and widespread epidemics in the swine population. However, the ecology, evolution, and spread of PEDV are still unclear. Here, from 149,869 fecal and intestinal tissue samples of pigs collected in an 11-year survey, we identified PEDV as the most dominant virus in diarrheal animals. Global whole genomic and evolutionary analyses of 672 PEDV strains revealed the fast-evolving PEDV genotype 2 (G2) strains as the main epidemic viruses worldwide, which seems to correlate with the use of G2-targeting vaccines. The evolving pattern of the G2 viruses presents geographic bias as they evolve…

Citation impact

184
total citations
FWCI
32.79
Percentile
100%
References
58
Citations per year

Authors

17

Topics & keywords

Topics
Keywords
  • Porcine epidemic diarrhea virus
  • Biology
  • Coronavirus
  • Virology
  • Transmission (telecommunications)
  • Haplotype
  • Genotype
  • Feces
UN Sustainable Development Goals
  • Good health and well-being
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