Clinical Impact of Staphylococcus aureus Skin and Soft Tissue Infections
Rutgers, The State University of New Jersey · Rutgers New Jersey Medical School · +1 more institution
Abstract
The pathogenic bacterium Staphylococcus aureus is the most common pathogen isolated in skin-and-soft-tissue infections (SSTIs) in the United States. Most S. aureus SSTIs are caused by the epidemic clone USA300 in the USA. These infections can be serious; in 2019, SSTIs with S. aureus were associated with an all-cause, age-standardized mortality rate of 0.5 globally. Clinical presentations of S. aureus SSTIs vary from superficial infections with local symptoms to monomicrobial necrotizing fasciitis, which can cause systemic manifestations and may lead to serious complications or death. In order to cause skin infections, S. aureus employs a host of virulence factors including cytolytic proteins, superantigenic…
Citation impact
- FWCI
- 45.05
- Percentile
- 100%
- References
- 260
Authors
4- MSMatthew S. Linz
Rutgers, The State University of New Jersey, Rutgers New Jersey Medical School
- AMArun Mattappallil
University Hospital, Newark
- DFDiana Finkel
Rutgers, The State University of New Jersey, Rutgers New Jersey Medical School
- DPDane ParkerCorresponding
Rutgers, The State University of New Jersey, Rutgers New Jersey Medical School
Topics & keywords
- Staphylococcus aureus
- Medicine
- Clindamycin
- Skin infection
- Staphylococcal Skin Infections
- Antibiotics
- Vancomycin
- Microbiology
- Good health and well-being