reviewInternational Journal of Molecular SciencesMar 10, 2023GOLD OA

Endocrine-Disrupting Chemicals and Disease Endpoints

Jeju National University · Chungbuk National University

PubMed
Indexed incrossrefpubmed

Abstract

Endocrine-disrupting chemicals (EDCs) have significant impacts on biological systems, and have been shown to interfere with physiological systems, especially by disrupting the hormone balance. During the last few decades, EDCs have been shown to affect reproductive, neurological, and metabolic development and function and even stimulate tumor growth. EDC exposure during development can disrupt normal development patterns and alter susceptibility to disease. Many chemicals have endocrine-disrupting properties, including bisphenol A, organochlorines, polybrominated flame retardants, alkylphenols, and phthalates. These compounds have gradually been elucidated as risk factors for many diseases, such as…

Citation impact

212
total citations
FWCI
31.70
Percentile
100%
References
188
Citations per year

Authors

2

Topics & keywords

Keywords
  • Endocrine system
  • Disease
  • Endocrine disruptor
  • Endocrine disease
  • Biology
  • Hormone
  • Physiology
  • Medicine
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