Current understanding of plant-derived exosome-like nanoparticles in regulating the inflammatory response and immune system microenvironment
Xiangya Hospital Central South University · Central South University · +3 more institutions
Abstract
Natural compounds are widely used to prevent and treat various diseases due to their antioxidant and anti-inflammatory effects. As a kind of promising natural compound, plant-derived exosome-like nanoparticles (PELNs) are extracted from multivesicular bodies of various edible plants, including vegetables, foods, and fruits, and mainly regulate the cellular immune response to pathogen attacks. Moreover, PELNs could remarkably interfere with the dynamic imbalance between pro-inflammatory and anti-inflammatory effects, facilitating to maintain the homeostasis of cellular immune microenvironment. PELNs may serve as a better alternative to animal-derived exosomes (ADEs) owing to their widespread sources,…
Citation impact
- FWCI
- 28.97
- Percentile
- 100%
- References
- 147
Authors
7- QYQiaoli Yi
Xiangya Hospital Central South University, Central South University
- ZXZhijie Xu
Xiangya Hospital Central South University, Central South University
- ATAbhimanyu Thakur
University of Chicago
- KZKui Zhang
State Key Laboratory of Silkworm Genomic Biology, Southwest University
- QLQiuju Liang
Xiangya Hospital Central South University, Central South University
Topics & keywords
- Microvesicles
- Immune system
- Inflammation
- Biogenesis
- Exosome
- Biology
- Innate immune system
- Tumor microenvironment