reviewPharmaceuticalsMar 17, 2023GOLD OA

Properties of Poly (Lactic-co-Glycolic Acid) and Progress of Poly (Lactic-co-Glycolic Acid)-Based Biodegradable Materials in Biomedical Research

Yantai University

PubMed
Indexed incrossrefdoajpubmed

Abstract

In recent years, biodegradable polymers have gained the attention of many researchers for their promising applications, especially in drug delivery, due to their good biocompatibility and designable degradation time. Poly (lactic-co-glycolic acid) (PLGA) is a biodegradable functional polymer made from the polymerization of lactic acid (LA) and glycolic acid (GA) and is widely used in pharmaceuticals and medical engineering materials because of its biocompatibility, non-toxicity, and good plasticity. The aim of this review is to illustrate the progress of research on PLGA in biomedical applications, as well as its shortcomings, to provide some assistance for its future research development.

Citation impact

221
total citations
FWCI
20.92
Percentile
100%
References
113
Citations per year

Authors

6

Topics & keywords

Keywords
  • Glycolic acid
  • PLGA
  • Biocompatibility
  • Lactic acid
  • Biodegradable polymer
  • Drug delivery
  • Polymer
  • Materials science
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