Ultra‐Small High‐Entropy Alloy Nanoparticles: Efficient Nanozyme for Enhancing Tumor Photothermal Therapy
Peking University · Center for Life Sciences · +2 more institutions
Abstract
High-entropy alloys nanoparticles (HEANPs) are receiving extensive attention due to their broad compositional tunability and unlimited potential in bioapplication. However, developing new methods to prepare ultra-small high-entropy alloy nanoparticles (US-HEANPs) faces severe challenges owing to their intrinsic thermodynamic instability. Furthermore, there are few reports on studying the effect of HEANPs in tumor therapy. Herein, the fabricated PtPdRuRhIr US-HEANPs act as bifunctional nanoplatforms for the highly efficient treatment of tumors. The US-HEANPs are engineered by the universal metal-ligand cross-linking strategy. This simple and scalable strategy is based on the aldol condensation of…
Citation impact
- FWCI
- 19.69
- Percentile
- 100%
- References
- 56
Authors
8- YAYongjian AiCorresponding
Peking University, Center for Life Sciences, Tsinghua University
- MHMengqi He
Peking University, Center for Life Sciences, Tsinghua University
- SHSun Hua
Peking University, Center for Life Sciences, Northeastern University, Tsinghua University
- XJXiaomeng Jia
Peking University, Center for Life Sciences, Tsinghua University
- LWLei Wu
Peking University, Center for Life Sciences, Tsinghua University
Topics & keywords
- Photothermal therapy
- Materials science
- Nanoparticle
- Nanotechnology
- Bifunctional
- Alloy
- Hydrogen peroxide
- Fabrication