reviewEuropean Heart JournalApr 3, 2023HYBRID OA

Exercise benefits in cardiovascular diseases: from mechanisms to clinical implementation

PLPedro L. ValenzuelaLMLuis M RuilopeASAlejandro Santos‐LozanoMWMatthias WilhelmNKNicolle Kränkel

Universidad de Alcalá · Research Institute Hospital 12 de Octubre · +6 more institutions

PubMed
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Abstract

There is a pandemic of physical inactivity that appears to parallel the widespread prevalence of cardiovascular disease (CVD). Yet, regular physical activity (PA) and exercise can play an important role not only in primary cardiovascular prevention but also in secondary prevention. This review discusses some of the main cardiovascular effects of PA/exercise and the mechanisms involved, including a healthier metabolic milieu with attenuation of systemic chronic inflammation, as well as adaptations at the vascular (antiatherogenic effects) and heart tissue (myocardial regeneration and cardioprotection) levels. The current evidence for safe implementation of PA and exercise in patients with CVD is also…

Citation impact

202
total citations
FWCI
72.37
Percentile
100%
References
218
Citations per year

Authors

7

Topics & keywords

Topics
Keywords
  • Medicine
  • Cardioprotection
  • Disease
  • Physical activity
  • Intensive care medicine
  • Secondary prevention
  • Cardiorespiratory fitness
  • Physical therapy
UN Sustainable Development Goals
  • Good health and well-being
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