Role of gut microbiota in infectious and inflammatory diseases
Universidade Federal do Rio Grande do Sul · Hospital de Clínicas de Porto Alegre · +3 more institutions
Abstract
Thousands of microorganisms compose the human gut microbiota, fighting pathogens in infectious diseases and inhibiting or inducing inflammation in different immunological contexts. The gut microbiome is a dynamic and complex ecosystem that helps in the proliferation, growth, and differentiation of epithelial and immune cells to maintain intestinal homeostasis. Disorders that cause alteration of this microbiota lead to an imbalance in the host's immune regulation. Growing evidence supports that the gut microbial community is associated with the development and progression of different infectious and inflammatory diseases. Therefore, understanding the interaction between intestinal microbiota and the modulation…
Citation impact
- FWCI
- 30.24
- Percentile
- 100%
- References
- 246
Authors
8- MFMiriãn Ferrão Maciel-Fiuza
Universidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, National Institute on Population Medical Genetics
- GCGuilherme Cerutti Müller
Universidade Federal do Rio Grande do Sul
- DMDaniel Marques Stuart Campos
Universidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre
- PDPerpétua do Socorro Silva Costa
Universidade Federal do Rio Grande do Sul, National Institute on Population Medical Genetics, Universidade Federal do Maranhão
- JPJuliano Peruzzo
Universidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre
Topics & keywords
- Gut flora
- Biology
- Microbiology
- Microbiome
- Immunology
- Bioinformatics
- Life in Land
Funding
- CDCoordenação de Aperfeiçoamento de Pessoal de Nível SuperiorAward: 573993/2008-4
- CNConselho Nacional de Desenvolvimento Científico e TecnológicoAwards: 573993/2008-4, 312960/2021-2
- HDHospital de Clínicas de Porto Alegre
- FDFundação de Amparo à Pesquisa do Estado do Rio Grande do SulAwards: 19/2551, 17/2551.0000521-0
- FIFundação Instituto de Pesquisas Econômicas
- INInstituto Nacional de Genética Médica PopulacionalAwards: CNPq 573993/2008-4, FAPERGS 17/2551.0000521-0, 17/2551.0000521-0, 573993/2008-4