Long-Term Outcomes in IgA Nephropathy

University College London · Therapeutics Clinical Research · +5 more institutions

PubMed
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Abstract

Background

IgA nephropathy can progress to kidney failure, and risk assessment soon after diagnosis has advantages both for clinical management and the development of new therapeutics. We present relationships among proteinuria, eGFR slope, and lifetime risks for kidney failure.

Methods

The IgA nephropathy cohort (2299 adults and 140 children) of the UK National Registry of Rare Kidney Diseases (RaDaR) was analyzed. Patients enrolled had a biopsy-proven diagnosis of IgA nephropathy plus proteinuria >0.5 g/d or eGFR

Citation impact

374
total citations
FWCI
65.87
Percentile
100%
References
21
Citations per year

Authors

12

Topics & keywords

Keywords
  • Medicine
  • Proteinuria
  • Nephropathy
  • Internal medicine
  • Cohort
  • Proportional hazards model
  • Kidney disease
  • Renal function
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Funding