Green synthesis of multi-functional carbon dots from medicinal plant leaves for antimicrobial, antioxidant, and bioimaging applications

Gedda, Gangaraju; Sankaranarayanan, Sri Amruthaa; Putta, Chandra Lekha; Gudimella, Krishna Kanthi; Rengan, Aravind Kumar; Girma, Wubshet Mekonnen

doi:10.1038/s41598-023-33652-8

articleScientific ReportsApr 19, 2023GOLD OA

Green synthesis of multi-functional carbon dots from medicinal plant leaves for antimicrobial, antioxidant, and bioimaging applications

GGGangaraju Gedda SASri Amruthaa Sankaranarayanan CLChandra Lekha Putta KKKrishna Kanthi Gudimella AKAravind Kumar Rengan

Presidency University · Indian Institute of Technology Hyderabad · +2 more institutions

PubMed

Indexed incrossrefdoajpubmed

Abstract

Abstract In this research work, carbon dots (CDs) were synthesized from the renewable leaves of an indigenous medicinal plant by the one-pot sand bath method, Azadirachta indica . The synthesized CDs were characterized for its optical properties using UV–Vis, Fluorescence and Fourier transform infrared (FT-IR) spectrophotometry and for structural properties using dynamic light scattering (DLS), X-ray Diffraction (XRD) and high resolution Transmission electron microscopy (HR-TEM). The synthesized CDs exhibited concentration dependent biocompatibility when tested in mouse fibroblast L929 cell line. The EC 50 values of biomedical studies, free radical scavenging activity (13.87 μgmL −1 ), and total antioxidant…

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Topics

Keywords

Biocompatibility
Antimicrobial
Nuclear chemistry
Antioxidant
Fluorescence
Fourier transform infrared spectroscopy
Azadirachta
Chemistry

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