Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing
Tongren Hospital · Wuhan Third Hospital · +5 more institutions
Abstract
Wound healing is a dynamic and highly sequential process involving a series of overlapping spatial and temporal phases, including hemostasis, inflammation, proliferation, and tissue remodeling. Mesenchymal stem cells (MSCs) are multipotent stem cells with self-renewal, multidirectional differentiation potential, and paracrine regulation. Exosomes are subcellular vesicular components 30-150 nm in size and are novel carriers of intercellular communication in regulating the biological behaviors of skin cells. Compared to MSCs, MSC-derived exosomes (MSC-exos) possess lower immunogenicity, easy storage, and highly effective biological activity. MSC-exos, mainly derived from adipose-derived stem cells (ADSCs), bone…
Citation impact
- FWCI
- 42.74
- Percentile
- 100%
- References
- 114
Authors
8- CZChuchao Zhou
Tongren Hospital, Wuhan Third Hospital
- BZBoyu Zhang
Tongji Hospital, Huazhong University of Science and Technology
- YYYanqing Yang
Tongren Hospital, Wuhan Third Hospital
- QJQiong Jiang
Xianning Central Hospital, Hubei University of Science and Technology
- TLTianyu Li
Tongji Hospital, Huazhong University of Science and Technology
Topics & keywords
- Stem cell
- Microvesicles
- Wound healing
- Biology
- Medicine
- Cell biology
- Immunology
- microRNA
- Good health and well-being