reviewJournal of Functional BiomaterialsApr 26, 2023GOLD OA

Effect of Size, Shape and Surface Functionalization on the Antibacterial Activity of Silver Nanoparticles

AMArianna MenichettiAMAlexandra Mavridi‐PrinteziDMDario MordiniMMMarco Montalti

University of Bologna

PubMed
Indexed incrossrefdoajpubmed

Abstract

Silver nanoparticles (AgNPs) are the most investigated antibacterial agents against multidrug resistant (MDR) pathogens. They can lead to cellular death by means of different mechanisms, damaging several cell compartments, from the external membrane, to enzymes, DNA and proteins; this simultaneous attack amplifies the toxic effect on bacteria with respect to traditional antibiotics. The effectiveness of AgNPs against MDR bacteria is strongly correlated with their chemical and morphological properties, which influence the pathways involved in cellular damage. In this review, AgNPs' size, shape and modification by functional groups or other materials are reported, both to investigate the different synthetic…

Citation impact

450
total citations
FWCI
40.53
Percentile
100%
References
128
Citations per year

Authors

4

Topics & keywords

Topics
Keywords
  • Silver nanoparticle
  • Surface modification
  • Antibacterial activity
  • Bacteria
  • Nanotechnology
  • Materials science
  • Nanoparticle
  • Multiple drug resistance
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