Tucatinib plus trastuzumab for chemotherapy-refractory, HER2-positive, RAS wild-type unresectable or metastatic colorectal cancer (MOUNTAINEER): a multicentre, open-label, phase 2 study

Strickler, John H.; Cercek, Andrea; Siena, Salvatore; André, Thierry; Ng, Kimmie; Cutsem, Eric Van; Wu, Christina; Paulson, Andrew Scott; Hubbard, Joleen M.; Coveler, Andrew L.; Fountzilas, Christos; Kardosh, Adel; Kasi, Pashtoon Murtaza; Lenz, Heinz‐Josef; Ciombor, Kristen K.; Élez, Elena; Bajor, David L.; Cremolini, Chiara; Sanchez, Federico; Stecher, Michael; Feng, Wentao; Bekaii‐Saab, Tanios; Cutsem, Eric Van; Peeters, Marc; Evnde, Marc Van den; André, Thierry; Borg, Christophe; Sarabi, Matthieu; Ghiringhelli, François; Chibaudel, Benoist; Siena, Salvatore; Cremolini, Chiara; Zampino, Maria Giulia; Élez, Elena; Keranen, Susana R.; Salazar, Ramón; Alfonso, Pilar; Strickler, John H.; Cercek, Andrea; Ng, Kimmie; Wu, Christina; Paulson, Andrew Scott; Hubbard, Joleen M.; Coveler, Andrew L.; Fountzilas, Christos; Kardosh, Adel; Kasi, Pashtoon Murtaza; Lenz, Heinz‐Josef; Ciombor, Kristen K.; Bajor, David L.; Bekaii‐Saab, Tanios; Gbolahan, Olumide B.; Boland, Patrick M.; Berg, Daniel; Sanchez, Federico; Goggins, Timothy F.; Saeed, Anwar; Burris, Howard A.; Bendell, Johanna C.; Outlaw, Darryl; Tafur, Isaac; Shergill, Ardaman; Catenacci, Daniel V.T.; Gong, Jun; Garrido‐Laguna, Ignacio; Finley, Gene Grant; Weinberg, Benjamin A.; Shields, Anthony F.; Philip, Philip; Turk, Anita; Nguyen, Anthony; Braiteh, Fadi; Patel, Vijay; Harwin, William; Anderson, Ian; Kundra, Ajay; Chen, Christopher S.; Ford, James M.; Kundranda, Madappa N.; Nguyen, Danny; Ratnam, Suresh; Richards, Donald; Nallapareddy, Sujatha; Beeram, Sridhar; McKenney, Scott; Shao, Spencer H.

doi:10.1016/s1470-2045(23)00150-x

articleThe Lancet OncologyMay 1, 2023GREEN OA

Tucatinib plus trastuzumab for chemotherapy-refractory, HER2-positive, RAS wild-type unresectable or metastatic colorectal cancer (MOUNTAINEER): a multicentre, open-label, phase 2 study

JHJohn H. Strickler ACAndrea Cercek SSSalvatore Siena TAThierry André KNKimmie Ng

Duke Medical Center · Memorial Sloan Kettering Cancer Center · +26 more institutions

PubMed

Indexed incrossrefpubmed

Abstract

No abstract available for this paper.

Citation impact

239

total citations

FWCI: 51.74
Percentile: 100%
References: 23

Citations per year

Authors

JH
John H. Strickler
Duke Medical Center
AC
Andrea Cercek
Memorial Sloan Kettering Cancer Center
SS
Salvatore Siena
University of Milan, Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
TA
Thierry André
Sorbonne Université, Hôpital Saint-Antoine
KN
Kimmie Ng
Dana-Farber Cancer Institute

Topics & keywords

Topics

HER2/EGFR in Cancer Research53%
Colorectal Cancer Treatments and Studies45%
Gastric Cancer Management and Outcomes0%

Keywords

Medicine
Internal medicine
Cohort
Trastuzumab
Colorectal cancer
Clinical endpoint
Interim analysis
Oncology

UN Sustainable Development Goals

Good health and well-being

No related works found for this paper.

Funding

M
Merck