articleNucleic Acids ResearchMay 4, 2023GOLD OA

PAE viewer: a webserver for the interactive visualization of the predicted aligned error for multimer structure predictions and crosslinks

CEChristoph ElfmannJSJörg Stülke

University of Göttingen

PubMed
Indexed incrossrefdoajpubmed

Abstract

The development of AlphaFold for protein structure prediction has opened a new era in structural biology. This is even more the case for AlphaFold-Multimer for the prediction of protein complexes. The interpretation of these predictions has become more important than ever, but it is difficult for the non-specialist. While an evaluation of the prediction quality is provided for monomeric protein predictions by the AlphaFold Protein Structure Database, such a tool is missing for predicted complex structures. Here, we present the PAE Viewer webserver (http://www.subtiwiki.uni-goettingen.de/v4/paeViewerDemo), an online tool for the integrated visualization of predicted protein complexes using a 3D structure…

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Topics & keywords

Topics
Keywords
  • Visualization
  • Web server
  • Metric (unit)
  • Biology
  • Computer science
  • Representation (politics)
  • Protein structure prediction
  • Quality (philosophy)
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