articleWorld PsychiatryMay 9, 2023BRONZE OA

Candidate biomarkers in psychiatric disorders: state of the field

AAAnissa Abi‐DarghamSJScott J. MoellerFAFarzana AliCDChristine DeLorenzoKDKatharina Domschke

Stony Brook School · Stony Brook University · +11 more institutions

PubMed
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Abstract

The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can aid in objectively diagnosing patients and providing individualized treatment recommendations. Here we review and critically evaluate the evidence for the most promising biomarkers in the psychiatric neuroscience literature for autism spectrum disorder, schizophrenia, anxiety disorders and post-traumatic stress disorder, major depression and bipolar disorder, and substance use disorders. Candidate biomarkers reviewed include various neuroimaging, genetic, molecular and peripheral assays, for the purposes of determining susceptibility or presence of illness, and predicting treatment response or safety. This review…

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Topics & keywords

Topics
Keywords
  • Anxiety
  • Neuroimaging
  • Medicine
  • Schizophrenia (object-oriented programming)
  • Autism spectrum disorder
  • Psychiatry
  • Bipolar disorder
  • Major depressive disorder
UN Sustainable Development Goals
  • Partnerships for the goals
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