Advances in spatial transcriptomics and related data analysis strategies

Spatial transcriptomics technologies developed in recent years can provide various information including tissue heterogeneity, which is fundamental in biological and medical research, and have been making significant breakthroughs. Single-cell RNA sequencing (scRNA-seq) cannot provide spatial information, while spatial transcriptomics technologies allow gene expression information to be obtained from intact tissue sections in the original physiological context at a spatial resolution. Various biological insights can be generated into tissue architecture and further the elucidation of the interaction between cells and the microenvironment. Thus, we can gain a general understanding of histogenesis processes and…

• SJ
  Shanghai Jiao Tong University
• S
  Servier
• SS
  Shanghai Shenkang Hospital Development Center

  Award: No. SHDC2020CR2070B