reviewBiomoleculesMay 8, 2023GOLD OA

Selenium and Selenoproteins in Health

FZFan ZhangXLXue‐Lian LiYWYumiao Wei

Union Hospital · Huazhong University of Science and Technology

PubMed
Indexed incrossrefdoajpubmed

Abstract

Selenium is a trace mineral that is essential for health. After being obtained from food and taken up by the liver, selenium performs various physiological functions in the body in the form of selenoproteins, which are best known for their redox activity and anti-inflammatory properties. Selenium stimulates the activation of immune cells and is important for the activation of the immune system. Selenium is also essential for the maintenance of brain function. Selenium supplements can regulate lipid metabolism, cell apoptosis, and autophagy, and have displayed significant alleviating effects in most cardiovascular diseases. However, the effect of increased selenium intake on the risk of cancer remains unclear.…

Citation impact

321
total citations
FWCI
48.33
Percentile
100%
References
268
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Authors

3

Topics & keywords

Topics
Keywords
  • Selenium
  • Immune system
  • Antioxidant
  • Autophagy
  • Selenium deficiency
  • Diabetes mellitus
  • Chemistry
  • Apoptosis
UN Sustainable Development Goals
  • Good health and well-being
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