articleNatureMay 31, 2023HYBRID OA

Enhanced rare-earth separation with a metal-sensitive lanmodulin dimer

Pennsylvania State University · Lawrence Livermore National Laboratory · +1 more institution

PubMed
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Abstract

Abstract Technologically critical rare-earth elements are notoriously difficult to separate, owing to their subtle differences in ionic radius and coordination number 1–3 . The natural lanthanide-binding protein lanmodulin (LanM) 4,5 is a sustainable alternative to conventional solvent-extraction-based separation 6 . Here we characterize a new LanM, from Hansschlegelia quercus ( Hans -LanM), with an oligomeric state sensitive to rare-earth ionic radius, the lanthanum(III)-induced dimer being >100-fold tighter than the dysprosium(III)-induced dimer. X-ray crystal structures illustrate how picometre-scale differences in radius between lanthanum(III) and dysprosium(III) are propagated to Hans -LanM’s…

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