reviewPharmaceuticsMay 31, 2023GOLD OA

Biomarkers as Biomedical Bioindicators: Approaches and Techniques for the Detection, Analysis, and Validation of Novel Biomarkers of Diseases

University of Calgary · Foothills Medical Centre · +2 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

A biomarker is any measurable biological moiety that can be assessed and measured as a potential index of either normal or abnormal pathophysiology or pharmacological responses to some treatment regimen. Every tissue in the body has a distinct biomolecular make-up, which is known as its biomarkers, which possess particular features, viz., the levels or activities (the ability of a gene or protein to carry out a particular body function) of a gene, protein, or other biomolecules. A biomarker refers to some feature that can be objectively quantified by various biochemical samples and evaluates the exposure of an organism to normal or pathological procedures or their response to some drug interventions. An…

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325
total citations
FWCI
61.60
Percentile
100%
References
177
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Authors

3

Topics & keywords

Keywords
  • Biomarker
  • Computational biology
  • Biomarker discovery
  • Metabolomics
  • Bioinformatics
  • Epigenetics
  • Medicine
  • Computer science
UN Sustainable Development Goals
  • Good health and well-being
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