Association between triglyceride-glucose index and all-cause mortality in critically ill patients with ischemic stroke: analysis of the MIMIC-IV database

Abstract Background The triglyceride-glucose (TyG) index was significantly associated with insulin resistance (IR). Several studies have validated the effect of TyG index on cerebrovascular disease. However, the value of TyG index in patients with severe stroke requiring ICU admission remains unclear. The aim of this study was to investigate the association between the TyG index and clinical prognosis of critically ill patients with ischemic stroke (IS). Methods This study identified patients with severe IS requiring ICU admission from the Medical Information Mart for Intensive Care (MIMIC-IV) database, and divided them into quartiles based on TyG index level. The outcomes included in-hospital mortality and…

• NN
  National Natural Science Foundation of China

  Awards: 81970527, No. 81970527
• WM
  Wenzhou Municipal Science and Technology Bureau

  Awards: No. Y20220024, Y20220024
• NS
  Natural Science Foundation of Zhejiang Province

  Award: Y23H030023