Recent advances on 3D-printed PCL-based composite scaffolds for bone tissue engineering
Shahroud University of Medical Sciences · Universal Scientific Education and Research Network · +2 more institutions
Abstract
Population ageing and various diseases have increased the demand for bone grafts in recent decades. Bone tissue engineering (BTE) using a three-dimensional (3D) scaffold helps to create a suitable microenvironment for cell proliferation and regeneration of damaged tissues or organs. The 3D printing technique is a beneficial tool in BTE scaffold fabrication with appropriate features such as spatial control of microarchitecture and scaffold composition, high efficiency, and high precision. Various biomaterials could be used in BTE applications. PCL, as a thermoplastic and linear aliphatic polyester, is one of the most widely used polymers in bone scaffold fabrication. High biocompatibility, low cost, easy…
Citation impact
- FWCI
- 19.62
- Percentile
- 100%
- References
- 201
Authors
7- MGMaliheh Gharibshahian
Shahroud University of Medical Sciences
- MSMajid Salehi
Shahroud University of Medical Sciences
- NBNima Beheshtizadeh
Universal Scientific Education and Research Network, Tehran University of Medical Sciences
- MKMohammad Kamalabadi‐Farahani
Shahroud University of Medical Sciences
- AAAmir Atashi
Shahroud University of Medical Sciences
Topics & keywords
- Scaffold
- 3d printed
- Materials science
- Biocompatibility
- Biomedical engineering
- Polycaprolactone
- 3D printing
- Bone tissue