reviewPharmaceuticsJun 23, 2023GOLD OA

Triple Negative Breast Cancer Treatment Options and Limitations: Future Outlook

Howard University

PubMed
Indexed incrossrefdoajpubmed

Abstract

Triple negative breast cancer (TNBC) has a negative expression of estrogen receptors (ER), progesterone receptors (PR), and human epidermal growth factor receptors (HER2). The survival rate for TNBC is generally worse than other breast cancer subtypes. TNBC treatment has made significant advances, but certain limitations remain. Treatment for TNBC can be challenging since the disease has various molecular subtypes. A variety of treatment options are available, such as chemotherapy, immunotherapy, radiotherapy, and surgery. Chemotherapy is the most common of these options. TNBC is generally treated with systemic chemotherapy using drugs such as anthracyclines and taxanes in neoadjuvant or adjuvant settings.…

Citation impact

391
total citations
FWCI
95.26
Percentile
100%
References
167
Citations per year

Authors

3

Topics & keywords

Keywords
  • Triple-negative breast cancer
  • Medicine
  • Breast cancer
  • Radiation therapy
  • Immunotherapy
  • Chemotherapy
  • Oncology
  • Targeted therapy
UN Sustainable Development Goals
  • Good health and well-being
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