reviewPreprints.orgJun 27, 2023GREEN OA

Origin of Antibiotics and Antibiotic Resistance, and Their Impacts on Drug Development: A Narrative Review

King Faisal University · Ajman University · +1 more institution

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Abstract

Antibiotic resistance has emerged as one of the major concerns to public human health due to issues in treatment and control of major infectious diseases. From discovery of penicillin in 1940, the antibiotic resistance originated and now developed the microorganisms as resistive strains to the major available antibiotics. Furthermore, studies on this captivating activity of the microbes provide insight into the complexities of microbial physiology and may offer some guidance in preventing the onset and consequent development of antibiotic resistance. Despite of initiatives taken in last few decades to overcome the issues, the trends of antibiotic resistance gained much peak. Antibiotic resistance appears to…

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202
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Authors

4

Topics & keywords

Keywords
  • Antibiotics
  • Antibiotic resistance
  • Drug resistance
  • Intensive care medicine
  • Drug development
  • Penicillin
  • Resistance (ecology)
  • Biotechnology
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