The role of CXCL family members in different diseases
Shanghai University of Traditional Chinese Medicine · Longhua Hospital Shanghai University of Traditional Chinese Medicine
Abstract
Chemokines are a large family mediating a lot of biological behaviors including chemotaxis, tumor growth, angiogenesis and so on. As one member of this family, CXC subfamily possesses the same ability. CXC chemokines can recruit and migrate different categories of immune cells, regulate tumor's pathological behaviors like proliferation, invasion and metastasis, activate angiogenesis, etc. Due to these characteristics, CXCL subfamily is extensively and closely associated with tumors and inflammatory diseases. As studies are becoming more and more intensive, CXCLs' concrete roles are better described, and CXCLs' therapeutic applications including biomarkers and targets are also deeply explained. In this review,…
Citation impact
- FWCI
- 56.13
- Percentile
- 100%
- References
- 142
Authors
5- CZChenjia ZhouCorresponding
Shanghai University of Traditional Chinese Medicine, Longhua Hospital Shanghai University of Traditional Chinese Medicine
- YGYing Gao
Shanghai University of Traditional Chinese Medicine
- PDPeilun Ding
Shanghai University of Traditional Chinese Medicine
- TWTao Wu
Shanghai University of Traditional Chinese Medicine
- GJGuang Ji
Shanghai University of Traditional Chinese Medicine, Longhua Hospital Shanghai University of Traditional Chinese Medicine
Topics & keywords
- Psychology
- Medicine
- Good health and well-being